State of the Science of Endocrine Disrupting Chemicals - 2012
Author:
The United Nations Environment Programme (UNEP) and the World Health Organization (WHO)
Date Published:
2012
Description:
The United Nations Environment Programme (UNEP) and WHO present an update of the IPCS (2002) document, entitled State of the Science of Endocrine Disrupting Chemicals—2012. This document
provides the global status of scientific knowledge on exposure to and effects of EDCs. It explains, in the first
chapter, what endocrine disruption is all about, and then it discusses in detail, in 12 sections in the second chapter, endocrine disrupting effects in humans and wildlife. The work is based on the fact that endocrine systems are very similar across vertebrate species and that endocrine effects manifest themselves independently of species. The effects are endocrine system related and not necessarily species
dependent. Effects shown in wildlife or experimental animals may also occur in humans if they are exposed to EDCs at a vulnerable time and at concentrations leading to alterations of endocrine regulation. Of special concern are effects on early development of both humans and wildlife, as these effects are often irreversible and may not become evident until later in life. The third and final chapter of this document discusses exposure of humans and wildlife to EDCs and potential EDCs.
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