Genotoxic effects in wild rodents (Rattus rattus and Mus musculus) in an open coal mining area
Author:
Grethel Leon, Lyda Espitia Perez, Juan Carlos Linares, Andreas Hartmann, Milton Quintana
Date Published:
03/2007
Description:
Coal is a mixture of a variety of compounds containing mutagenic and carcinogenic polycyclic aromatic hydrocarbons. Exposure to coal is considered as an important non-cellular and cellular source of reactive oxygen species that can induce DNA damage. In addition, spontaneous combustion can occur in coal mining areas, further releasing compounds with detrimental effects on the
environment. In this study the comet assay was used to investigate potential genotoxic effects of coal mining activities in peripheral
blood cells of the wild rodents Rattus rattus and Mus musculus.
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